Job Description

Job Description

Job Description

About Tonix*

Tonix is a fully integrated biotechnology company, publicly traded on NASDAQ (ticker: TNXP), with marketed products and a pipeline of development candidates The Company is focused on commercializing, developing, discovering, and licensing therapeutics to treat and prevent human disease. In August 2025, Tonix received FDA approval for Tonmya™ (cyclobenzaprine HCl sublingual tablets), a first-in-class, once-daily, non-opioid treatment for fibromyalgia. Tonmya is the first new fibromyalgia therapy approved in over 15 years, following successful Phase 3 trials demonstrating significant symptom improvement. Commercial launch is expected in the fourth quarter of 2025. Tonix also markets Zembrace® SymTouch® (sumatriptan injection) 3 mg and Tosymra® (sumatriptan nasal spray) 10 mg, both indicated for the treatment of acute migraine with or without aura in adults.

Tonix’s development portfolio includes product candidates in central nervous system (CNS), immunology, immuno-oncology infectious disease and rare disease. The CNS pipeline features both small molecules and biologics to treat pain, neurologic, psychiatric, and addiction conditions. The immunology portfolio includes biologics to address organ transplant rejection, autoimmunity, and cancer. The infectious disease pipeline includes a vaccine in development to prevent smallpox and monkeypox, which also serves as a live virus vaccine platform for other infectious diseases. Finally, the rare disease portfolio includes a product in development for Prader-Willi syndrome, which has both orphan drug designation and rare pediatric disease designation grants from the FDA.

Tonix owns and operates a state-of-the art infectious disease research facility in Frederick, Md.

Please visit for specifics on the pipeline.

*All of Tonix’s product candidates are investigational new drugs or biologics and have not been approved for any indication.

Position Overview

Tonix Pharmaceuticals is advancing a diverse portfolio of therapies, including biologics, small molecules, and vaccines in oncology, CNS, and immunological disorders. We are seeking a Scientist-II to expand our bioanalytical assay development capabilities, supporting programs from discovery through translational and regulatory milestones.

This role provides the opportunity to design and standardize robust bioanalytical and cell-based assays that directly support Tonix expanding pipeline, while generating high-quality data that drives preclinical and clinical decision-making

Key Responsibilities

• Bioanalytical Assay Development – Design, optimize, and validate assays for potency, neutralization, immunogenicity, biomarker detection, ADME/DMPK support, and oncology studies.
• Cell-Based Assay Innovation – Develop and refine functional cellular assays that model relevant biological responses.
• Non-Cell-Based Assay Development – Establish and optimize biochemical, biophysical, and label-free platforms (e.g., ELISA, MSD, Octet, enzymatic, and binding assays) to characterize drug potency, mechanism of action, and biomolecular interactions.
• Assay Lifecycle Execution – Drive feasibility studies, optimization, and assay qualification to support regulatory filings, translational research, and clinical sample analysis.
• Data Analysis & Reporting – Deliver accurate, reproducible datasets; prepare reports, SOPs, and regulatory documentation to support Tonix development programs.
• Compliance & Documentation – Ensure all work aligns with well documented standards, Tonix SOPs, and regulatory expectations.
• Portfolio Integration – Apply assay expertise to advance Tonix’s programs in any areas related to therapeutics and vaccines.

Required Qualifications

• Education: PhD (preferred) or master’s degree in Biochemistry, Molecular Biology, Cell Biology, Immunology, or related field.
• Bioanalytical Expertise: Proven track record developing and validating bioanalytical assays for potency, neutralizing antibodies, immunogenicity, and biomarkers.
• Assay Development Skills: Strong background in high-throughput and 384-well cell-based assay design, with applications in drug discovery and translational research
• Technical Skills: Proficiency in qPCR ELISA, MSD, high-content imaging, and automated assay workflows.
• Software Proficiency: Expertise in GraphPad Prism, and advanced bioanalysis/image analysis tools.
• Research Record: Publications in virology, antiviral discovery, and assay development that demonstrate impact and innovation
• Critical Thinking & Communication: Ability to interpret complex datasets and clearly communicate findings to scientific and non-scientific stakeholders.

Recruitment & Staffing Agencies

Tonix does not accept agency resumes unless contacted directly by internal Tonix Talent Acquisition. Please do not forward resumes to Tonix employees or any other company location; Tonix is not responsible for any fees related to unsolicited resumes.

Compensation & Benefits

Annualized base salary ranges from $70,000 to $120,000 plus target incentive; actual salaries will vary and may be above or below this range commensurate with several factors including experience, education, training, location, and merit.

Tonix provides a comprehensive compensation and benefits package which includes:

• Medical, Dental & Vision Insurance, Basic and Voluntary Life and AD&D Insurance, Short- and Long-Term Disability Insurance, Flexible Spending Accounts, Health Savings Account, and Employee Assistance Programs
• Pet Insurance
• Retirement Savings 401k with company match and annual discretionary stock options
• Generous Paid Time Off, Sick Time, & Paid Holidays
• Career Development and Training

Tonix provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, sex, national origin, age, genetics, or any other characteristic protected by law. In addition to federal law requirements, Tonix complies with applicable state and local laws governing nondiscrimination in employment. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfers, leaves of absence, compensation, and training. Tonix expressly prohibits any form of workplace harassment based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic, information, disability, veteran status, or any other characteristic protected by law.

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